Dupuytren's contracture is a disease of the middle volar aponeurosis causing fixed flexion deformities of one or several digits.
This autosomal dominant disease affects less than 5% of individuals in Northern European countries. Males are more often affected (80%) than females and the average age at onset is the fifth decade.
It is a real diathesis with possible similar fibrosis in finger (dorsal knuckle pads), feet (Ledderhose's disease) and penis (Peyronie's disease).
The prevalence is 30% higher in diabetics, 40% higher in epileptics. The incidence is increased by alcoholism, by phenobarbitone administration and possibly by regional injury.
Stages are defined using Tubiana's simplified criterias as follows :
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